L-Menthyl Lactate
L-Menthyl lactate
CAS: 61597-98-6
Molecular Formula: C13H24O3
L-Menthyl Lactate - Names and Identifiers
| Name | L-Menthyl lactate |
| Synonyms | L-Menthyl lactate L-(-)-Menthyl L-Lactate L-Menthyl Ester of Lactic Acid (1R,2S,5R)-2-Isopropyl-5-Methylcyclohexyl (S)-2-Hydroxypropionate (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (S)-2-Hydroxypropionate (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2S)-2-hydroxypropanoate (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (2S)-2-hydroxypropanoate Propanoic acid, 2-hydroxy-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester, (2S)- |
| CAS | 61597-98-6 |
| InChI | InChI=1/C13H24O3/c1-8(2)11-6-5-9(3)7-12(11)16-13(15)10(4)14/h8-12,14H,5-7H2,1-4H3/t9-,10+,11+,12-/m1/s1 |
L-Menthyl Lactate - Physico-chemical Properties
| Molecular Formula | C13H24O3 |
| Molar Mass | 228.33 |
| Density | 0.99±0.1 g/cm3(Predicted) |
| Melting Point | 42-47°C(lit.) |
| Boling Point | 142°C5mm Hg(lit.) |
| Specific Rotation(α) | -81 º (c=5,EtOH) |
| Flash Point | >230°F |
| JECFA Number | 433 |
| Vapor Presure | 0.003-0.007Pa at 20℃ |
| Appearance | Viscous |
| Color | White to Almost white |
| Maximum wavelength(λmax) | ['233nm(CH2Cl2)(lit.)'] |
| pKa | 13.01±0.20(Predicted) |
| Storage Condition | Room Temprature |
| Refractive Index | 1.467 |
| Physical and Chemical Properties | alpha:-81 o (c=5,EtOH) |
L-Menthyl Lactate - Risk and Safety
| WGK Germany | 3 |
L-Menthyl Lactate - Reference Information
| FEMA | 3748 | L-MENTHYL LACTATE |
| LogP | 3.629-3.641 at 25℃ and pH5.68-7.05 |
| Product description | L-menthyl lactate (L-Menthyl lactate) is a mint derivative with white needle-like crystals, almost no aroma, cool and lasting, with a cooling effect, is the best substitute for Mint, with long-lasting, tasteless, non-irritating characteristics, widely used in cosmetics, skin care products, washing products, tobacco, food, beverage, candy, mint water, medicine and other products, to overcome the limitations of the cooling products can only be mint flavor, the user can prepare a variety of flavor cooling products to suit different market concepts. In the application of cigarette products, so that smoking oral left fresh feeling, dosage: 0.005% ~ 0.05%. FEMA #3748. |
| preparation method | with menthol and L-lactic acid as raw materials, with cyclohexane with water, after esterification, L-menthyl lactate was refined, and the effects of reaction time, molar ratio of alcohol to acid and amount of catalyst on the reaction were studied. The preferential process conditions were determined as follows: n (menthol):n(L-lactic acid) = 1.2:1.0, the catalyst is 2% of the total weight of the raw material, cyclohexane is heated to reflux with water, reaction 6h, vacuum distillation to 120 ℃/400 PA. The residue is recrystallized, A white needle-like crystalline product was obtained with a yield of more than 80% and a purity of 99%. Affiliation: Hunan Institute of Pharmaceutical Industry, 2008no.3 < |
Last Update：2024-04-09 20:48:19
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View History
L-Menthyl Lactate
5-Pyrimidinecarboxylic acid, 2-(4-methylphenyl)- (9CI)
2-氯-6-(吡咯烷-1-基)苯(甲)醛
L-Tyrosine, 3-hydroxy-, Methyl ester
2-氟-3-碘代吡啶
双喹啉-4-羧酸二钠盐
SULFONATED POLYSTYRENE
2-((4-Fluorophenyl)Sulfonyl)Nicotinaldehyde(WXC03057)
1-Propylallyl alcohol
1-(2-hydroxy-5-tert-nonylphenyl)ethan-1-one oxime
5-Pyrimidinecarboxylic acid, 2-(4-methylphenyl)- (9CI)
2-氯-6-(吡咯烷-1-基)苯(甲)醛
L-Tyrosine, 3-hydroxy-, Methyl ester
2-氟-3-碘代吡啶
双喹啉-4-羧酸二钠盐
SULFONATED POLYSTYRENE
2-((4-Fluorophenyl)Sulfonyl)Nicotinaldehyde(WXC03057)
1-Propylallyl alcohol
1-(2-hydroxy-5-tert-nonylphenyl)ethan-1-one oxime